Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569965 | 0.92 | DDB1 (0.47) | CRBNDDB1DRD2GRM2DRD4 | |
| SCHEMBL31569639 | 0.85 | DDB1 (0.54) | CRBNDDB1 | |
| SCHEMBL31569618 | 0.82 | DDB1 (0.55) | CRBNDDB1 | |
| SCHEMBL31570018 | 0.77 | SOS1 (0.55) | CRBNDDB1 | |
| SCHEMBL31569599 | 0.76 | DDB1 (0.51) | CRBNDDB1 | |
| SCHEMBL31569855 | 0.76 | CRBN (0.44) | CRBNDDB1DRD4 | |
| SCHEMBL31569660 | 0.75 | DDB1 (0.55) | CRBNDDB1 | |
| SCHEMBL31569919 | 0.75 | CRBN (0.47) | CRBNDDB1 | |
| SCHEMBL25217869 | 0.75 | CRBN (0.64) | CRBNDDB1 | |
| SCHEMBL30830925 | 0.73 | CRBN (0.58) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101588-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |