Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 16/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 16/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569599 | 0.91 | DDB1 (0.51) | DDB1CRBNPOLB | |
| SCHEMBL31569946 | 0.85 | CRBN (0.49) | DDB1CRBN | |
| SCHEMBL31569727 | 0.81 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL31570006 | 0.77 | GPR119 (0.50) | DDB1CRBN | |
| SCHEMBL31569965 | 0.76 | DDB1 (0.47) | DDB1CRBN | |
| SCHEMBL31569846 | 0.76 | HTR3A (0.47) | DDB1CRBNPOLB | |
| SCHEMBL27225354 | 0.76 | CRBN (0.51) | DDB1CRBNPOLB | |
| SCHEMBL30883502 | 0.76 | CRBN (0.51) | DDB1CRBNPOLB | |
| SCHEMBL31569734 | 0.75 | CRBN (0.50) | DDB1CRBNPOLB | |
| SCHEMBL21876580 | 0.75 | CRBN (0.62) | DDB1CRBNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101588-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |