Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 10/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560675 | 0.83 | ALDH1A1 (0.48) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31570575 | 0.83 | PDE4A (0.48) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31570521 | 0.81 | PDE4A (0.56) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL844679 | 0.79 | MAPT (0.56) | MAPTGALR3THRBALDH1A1CYP1A2 | |
| SCHEMBL9913544 | 0.76 | MAPT (0.53) | MAPTGALR3THRBALDH1A1TDP1 | |
| SCHEMBL2551921 | 0.76 | TDP1 (0.53) | MAPTALDH1A1TDP1KMT2ACYP3A4 | |
| SCHEMBL2654454 | 0.75 | TDP1 (0.51) | MAPTALDH1A1TDP1KMT2ACYP3A4 | |
| SCHEMBL9106616 | 0.75 | MAPT (0.51) | MAPTGALR3THRBALDH1A1CYP1A2 | |
| SCHEMBL15157040 | 0.74 | MAPT (0.50) | MAPTGALR3THRBALDH1A1CYP1A2 | |
| SCHEMBL559921 | 0.74 | PDE4A (0.52) | MAPTPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099451-A1 | NEW COMPOUNDS AND METHODS | Transition Bio Limited (GB) | 2025-05-15 | — | — | WO | disclosed |