Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15954389 | 1.00 | PDE2A (0.43) | PDE2ALMNATP53HTTHTR2C | |
| SCHEMBL10039364 | 0.83 | RECQL (0.36) | PDE2ALMNAHTR2APSEN1PSEN2 | |
| SCHEMBL24869062 | 0.81 | PDE2A (0.48) | PDE2ALMNATP53HTTHTR2C | |
| SCHEMBL30134086 | 0.79 | MEN1 (0.40) | PDE2AHTR2CHTR2APSEN1PSEN2 | |
| SCHEMBL20818058 | 0.79 | MEN1 (0.40) | PDE2AHTR2CHTR2APSEN1PSEN2 | |
| SCHEMBL20817934 | 0.79 | PSEN1 (0.37) | HTR2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31574267 | 0.79 | PSEN1 (0.37) | HTR2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1761854 | 0.78 | PDE2A (0.60) | PDE2ALMNATP53HTTHTR2C | |
| SCHEMBL18588971 | 0.78 | PSEN1 (0.46) | PDE2ALMNATP53HTTHTR2C | |
| SCHEMBL12040771 | 0.78 | RECQL (0.36) | LMNAHTR2APSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113939295-B | Pyridazinones and methods of use thereof | 金翅雀生物公司 | 2025-05-16 | — | — | CN | disclosed |