Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176646 | 1.00 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL176647 | 1.00 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL3157487 | 1.00 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL13871593 | 0.99 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL2715604 | 0.99 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL4101733 | 0.99 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL4101730 | 0.99 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL3087438 | 0.96 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL3087440 | 0.96 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL176533 | 0.95 | CNR2 (0.70) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851498-B2 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-14 | — | — | US | claimed |
| US-7825151-B2 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-02 | — | — | US | claimed |
| EP-1931335-B1 | HEXAHYDRO CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-02-24 | — | — | EP | claimed |
| EP-1931335-A1 | HEXAHYDRO CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-18 | — | — | EP | claimed |
| US-20080076814-A1 | Hexahydro-Cyclooctyl Pyrazole Cannabinoid Modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-27 | — | — | US | claimed |
| US-20070129417-A1 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | claimed |
| WO-2007044215-A1 | HEXAHYDRO CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-04-19 | — | — | WO | claimed |
| US-8101592-B2 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BG) | 2012-01-24 | — | — | US | disclosed |
| US-8101592-B2 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BG) | 2012-01-24 | — | — | US | disclosed |
| US-20100317633-A1 | HEXAHYDRO-CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-16 | — | — | US | disclosed |
| US-20100317633-A1 | HEXAHYDRO-CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-16 | — | — | US | disclosed |
| US-7851498-B2 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-14 | — | — | US | disclosed |
| US-7851498-B2 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-14 | — | — | US | disclosed |
| EP-1931335-A1 | HEXAHYDRO CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-18 | — | — | EP | disclosed |
| US-20080076814-A1 | Hexahydro-Cyclooctyl Pyrazole Cannabinoid Modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-27 | — | — | US | disclosed |
| US-20080076814-A1 | Hexahydro-Cyclooctyl Pyrazole Cannabinoid Modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-27 | — | — | US | disclosed |
| US-20070129417-A1 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | disclosed |
| US-20070129417-A1 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | disclosed |
| WO-2007044215-A1 | HEXAHYDRO CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044215-A1 | HEXAHYDRO CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317633-A1 | HEXAHYDRO-CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS | CNR1, CNR2, FAAH | CNR1 1/4885CNR2 2/4885 |
| US-20070129417-A1 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | CNR1, CNR2, FAAH | CNR1 1/4885CNR2 2/4885 |
| US-20080076814-A1 | Hexahydro-Cyclooctyl Pyrazole Cannabinoid Modulators | CNR1, CNR2, FAAH | CNR1 1/4885CNR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.