SCHEMBL31575412

SCHEMBL31575412

Cc1nc2c(c(=O)n(C)c(=O)n2C)n1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 5/20 0.60
KMT2A Q03164 4/20 0.50
RXFP1 Q9HBX9 2/20 0.50
ADORA2A P29274 4/20 0.49
PIK3CD O00329 1/20 0.49
POLB P06746 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
CNR1 P21554 1/20 0.49
ACHE P22303 1/20 0.49
ADORA1 P30542 1/20 0.49
NTSR1 P30989 1/20 0.49
MC3R P41968 1/20 0.49
NOTUM Q6P988 1/20 0.49
SIRT3 Q9NTG7 1/20 0.49
GDA Q9Y2T3 1/20 0.49
NR2E1 Q9Y466 1/20 0.49
CYP2C19 P33261 1/20 0.47
MAPT P10636 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2704481 0.82 KMT2A (0.59) ADORA2BKMT2ARXFP1ADORA2ACYP2C19
SCHEMBL3455609 0.77 ADORA2B (0.52) ADORA2BKMT2ARXFP1CYP2C19TSHR
SCHEMBL2403877 0.76 ADORA2B (0.69) ADORA2BKMT2ARXFP1ADORA2ACYP2C19
SCHEMBL9972884 0.75 KMT2A (0.56) ADORA2BKMT2ARXFP1ADORA2ACYP2C19
SCHEMBL7553023 0.75 TSHR (0.51) ADORA2BKMT2ARXFP1POLBCYP2C19
SCHEMBL4379838 0.75 TSHR (0.57) KMT2ARXFP1CYP2C19MAPTTSHR
SCHEMBL17626147 0.74 ADORA2B (0.54) ADORA2BRXFP1ADORA2ACYP2C19TSHR
SCHEMBL28223972 0.73 KMT2A (0.58) ADORA2BKMT2ARXFP1ADORA2ACYP2C19
SCHEMBL10668187 0.73 KMT2A (0.58) ADORA2BKMT2ARXFP1ADORA2ACYP2C19
SCHEMBL17626175 0.73 KMT2A (0.49) ADORA2BKMT2ARXFP1ADORA2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004898-A Compound containing aromatic ring or alicyclic ring and having anti-coronavirus activity and application thereof 中国医学科学院医药生物技术研究所 2025-05-16 CN disclosed