Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.32 |
| ▸ | CHRNG | P07510 | 2/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | CHRND | Q07001 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315758 | 1.00 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP2A6CYP3A4CYP2C9 | |
| SCHEMBL316756 | 0.93 | KDM4E (0.32) | CYP2C9CYP2C19ALDH1A1KDM4EMAPT | |
| SCHEMBL316757 | 0.93 | KDM4E (0.32) | CYP2C9CYP2C19ALDH1A1KDM4EMAPT | |
| SCHEMBL2142546 | 0.91 | KDM4E (0.34) | CYP11B1CYP11B2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2142538 | 0.91 | KDM4E (0.34) | CYP11B1CYP11B2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL315596 | 0.90 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL315595 | 0.90 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2410997 | 0.89 | CHRNB4 (0.42) | CYP11B1CYP11B2CYP2A6CYP3A4CYP2C9 | |
| SCHEMBL2411000 | 0.89 | CHRNB4 (0.42) | CYP11B1CYP11B2CYP2A6CYP3A4CYP2C9 | |
| SCHEMBL316525 | 0.87 | CYP2A6 (0.34) | CYP11B1CYP11B2CYP2A6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093394-B2 | Derivatives of 5-thioxylopyranose and use of same for treatment | LABORATOIRES FOURNIER S.A. (FR) | 2012-01-10 | — | — | US | disclosed |
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |
| US-20090182013-A1 | Derivatives of 5-Thioxylopyranose and Use of Same for Treatment | LABORATOIRES FOURNIER S.A. (FR) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182013-A1 | Derivatives of 5-Thioxylopyranose and Use of Same for Treatment | TPMT, PNPO, PPOX | CYP11B1 295/4885CYP11B2 261/4885CYP2A6 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.