SCHEMBL315765

SCHEMBL315765

Nc1ccc([N+](=O)[O-])cc1S(=O)(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 2/20 0.59
GAA P10253 2/20 0.55
THRB P10828 1/20 0.55
TDP1 Q9NUW8 4/20 0.53
ALDH1A1 P00352 6/20 0.52
CYP3A4 P08684 4/20 0.52
TSHR P16473 2/20 0.50
ALOX15 P16050 2/20 0.50
S1PR4 O95977 1/20 0.50
LMNA P02545 1/20 0.50
RAB9A P51151 1/20 0.50
HTT P42858 1/20 0.47
CYP2C19 P33261 1/20 0.47
PDE2A O00408 1/20 0.46
PDE5A O76074 1/20 0.46
NFKB1 P19838 1/20 0.46
APEX1 P27695 1/20 0.46
PDE4A P27815 1/20 0.46
BLM P54132 1/20 0.46
PDE1B Q01064 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67062 1.00 NT5E (0.59) NT5EGAATHRBTDP1ALDH1A1
Ammonia Solution, Strong SCHEMBL5566240 0.98 NT5E (0.57) NT5EGAATHRBTDP1ALDH1A1
Ammonia Solution, Strong SCHEMBL5566229 0.98 NT5E (0.57) NT5EGAATHRBTDP1ALDH1A1
Fluoride SCHEMBL11674539 0.98 NT5E (0.57) NT5EGAATHRBTDP1ALDH1A1
SCHEMBL715241 0.98 NT5E (0.57) NT5EGAATHRBTDP1ALDH1A1
SCHEMBL715240 0.98 NT5E (0.57) NT5EGAATHRBTDP1ALDH1A1
SCHEMBL715238 0.98 NT5E (0.57) NT5EGAATHRBTDP1ALDH1A1
Ammonia Solution, Strong SCHEMBL29104708 0.96 NT5E (0.56) NT5EGAATHRBTDP1ALDH1A1
SCHEMBL1485915 0.87 GAA (0.58) NT5EGAATHRBTDP1ALDH1A1
SCHEMBL9636142 0.85 CYP3A4 (0.60) NT5EGAATHRBTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116603464-B High-density epoxy resin microcapsule and preparation method and application thereof 武汉中科先进材料科技有限公司 2024-01-02 CN claimed
CN-116603464-A High-density epoxy resin microcapsule and preparation method and application thereof 武汉中科先进材料科技有限公司 2023-08-18 CN claimed
CN-116103711-A Forward and reverse pulse electrolytic nickel-phosphorus alloy solution, preparation method, electroplating method and nickel-phosphorus alloy coating 安徽智备工业科技有限公司 2023-05-12 CN claimed
EP-4673495-A1 FOAMABLE REACTION MIXTURE FOR MANUFACTURING OF FIRE PROTECTION PREFORMED ARTICLES, FIRE PROTECTION PREFORMED ARTICLE AND METHOD FOR MANUFACTURING OF FIRE PROTECTION PREFORMED ARTICLES Hilti Aktiengesellschaft (LI) 2026-01-07 EP disclosed
US-20250221408-A1 COMPOSITION EARTH CORPORATION (JP) 2025-07-10 US disclosed
CN-119955323-A High-fastness Baolan reactive dye and preparation method and application thereof 湖北丽源科技股份有限公司 2025-05-09 CN disclosed
WO-2025027985-A1 COMPOSITION, BLACK MATRIX, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND DISPLAY DEVICE 株式会社ADEKA 2025-02-06 WO disclosed
EP-4473837-A1 COMPOSITION Earth Corporation (JP) 2024-12-11 EP disclosed
WO-2024180070-A1 FOAMABLE REACTION MIXTURE FOR MANUFACTURING OF FIRE PROTECTION PREFORMED ARTICLES, FIRE PROTECTION PREFORMED ARTICLE AND METHOD FOR MANUFACTURING OF FIRE PROTECTION PREFORMED ARTICLES HILTI AKTIENGESELLSCHAFT (LI) 2024-09-06 WO disclosed
CN-111868630-B Colored curable resin composition, color filter and display device 东友精细化工有限公司 2024-04-09 CN disclosed
CN-115151591-B Composition, cured product, and method for producing cured product 株式会社艾迪科 2024-03-01 CN disclosed
EP-1826244-A1 INDOLIUM COMPOUNDS AND OPTICAL RECORDING MATERIALS Adeka Corporation (JP) 2007-08-29 EP disclosed
EP-1798261-A1 CYANINE COMPOUNDS AND OPTICAL RECORDING MATERIALS Adeka Corporation (JP) 2007-06-20 EP disclosed
EP-1795525-A1 HETEROCYCLIC COMPOUNDS AND OPTICAL RECORDING MATERIALS Adeka Corporation (JP) 2007-06-13 EP disclosed
US-20060286483-A1 Cyanine compounds, optical recording materials and optical recording media ASAHI DENKA CO., LTD. (JP) 2006-12-21 US disclosed
EP-1652892-A1 CYANINE COMPOUNDS, OPTICAL RECORDING MATERIALS AND OPTICAL RECORDING MEDIA Asahi Denka Co., Ltd. (JP) 2006-05-03 EP disclosed
CN-1732414-A Novel polyhydroxyalkanoate having amide, sulfonic acid or sulfonate ester group, charge control agent and toner CANON KK (JP) 2006-02-08 CN disclosed
US-20050031993-A1 Cyanine compound, optical recording material, and optical recording medium ASAHI DENKA CO., LTD. (JP) 2005-02-10 US disclosed
EP-1505125-A1 Cyanine compound, optical recording material, and optical recording medium Asahi Denka Co., Ltd. (JP) 2005-02-09 EP disclosed
US-4061812-A Honeycomb-laminate composite structure THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1977-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250221408-A1 COMPOSITION GGPS1, PGGT1B, HBG2 NT5E 4705/4885GAA 3820/4885THRB 2584/4885
US-20050031993-A1 Cyanine compound, optical recording material, and optical recording medium CHRM1, KCNB1, KCNB2 NT5E 2377/4885GAA 4740/4885THRB 3068/4885
US-20060286483-A1 Cyanine compounds, optical recording materials and optical recording media CHRM1, CRY2, KCNN1 NT5E 1695/4885GAA 4761/4885THRB 3364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.