Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31576807 | 0.82 | MEN1 (0.54) | CYP3A4MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL31576808 | 0.82 | RIPK2 (0.47) | CYP3A4MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL13922241 | 0.80 | ALOX5 (0.52) | CYP3A4MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL29405771 | 0.79 | ALOX5 (0.57) | CYP3A4MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL316240 | 0.78 | ALOX5 (0.56) | CYP3A4MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL819253 | 0.76 | ALOX5 (0.78) | CYP3A4MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL31576822 | 0.75 | ALOX5 (0.53) | CYP3A4MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL817774 | 0.75 | ALOX5 (0.53) | CYP3A4MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL23155161 | 0.74 | ALOX5 (0.61) | CYP3A4MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL6269604 | 0.73 | TRPV1 (0.42) | MEN1KMT2AKDM4EALOX5AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104281-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-05-22 | — | — | WO | disclosed |
| EP-4556004-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | Centre National de la Recherche Scientifique (FR) | 2025-05-21 | — | — | EP | disclosed |