Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | WEE1 | P30291 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29173404 | 0.85 | MAPK10 (0.40) | — | |
| SCHEMBL29173301 | 0.83 | BTK (0.39) | — | |
| SCHEMBL31577249 | 0.83 | WEE1 (0.31) | WEE1 | |
| SCHEMBL30206216 | 0.82 | EGFR (0.33) | — | |
| SCHEMBL29173389 | 0.82 | EGFR (0.33) | — | |
| SCHEMBL31577230 | 0.81 | FGFR4 (0.36) | WEE1 | |
| Formic Acid SCHEMBL30205747 | 0.81 | BTK (0.37) | — | |
| SCHEMBL31577209 | 0.79 | WEE1 (0.35) | WEE1 | |
| SCHEMBL29173642 | 0.78 | SYK (0.38) | — | |
| SCHEMBL31577202 | 0.77 | CDK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373817-B1 | SUBSTITUTED PYRAZINE-2-CARBOXAMIDES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2025-05-21 | — | — | EP | claimed |