Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.50 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828444 | 0.88 | CRBN (0.55) | CRBNDDB1GSPT1POLBNPC1 | |
| SCHEMBL25207570 | 0.87 | CRBN (0.48) | CRBNDDB1GSPT1POLB | |
| SCHEMBL31355995 | 0.87 | CRBN (0.48) | CRBNDDB1GSPT1POLBNPC1 | |
| SCHEMBL31579577 | 0.86 | CRBN (0.52) | CRBNDDB1GSPT1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL30938121 | 0.86 | CRBN (0.50) | CRBNDDB1GSPT1POLBNPC1 | |
| Hydrochloric Acid SCHEMBL30938132 | 0.85 | CRBN (0.49) | CRBNDDB1GSPT1POLBNPC1 | |
| SCHEMBL30828415 | 0.84 | CRBN (0.55) | CRBNDDB1GSPT1POLB | |
| SCHEMBL24821083 | 0.83 | CRBN (0.52) | CRBNDDB1GSPT1ALDH1A1NPC1 | |
| SCHEMBL30828446 | 0.83 | CRBN (0.57) | CRBNDDB1GSPT1ALDH1A1POLB | |
| SCHEMBL27411381 | 0.83 | CRBN (0.57) | CRBNDDB1GSPT1POLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163066-A1 | PROTACs of MALT1 | TEGID THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163066-A1 | PROTACs of MALT1 | MALT1, BCL3, BCL9 | CRBN 6/4885DDB1 430/4885GSPT1 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.