Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.55 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27411381 | 0.88 | CRBN (0.57) | CRBNDDB1GSPT1POLB | |
| SCHEMBL30828446 | 0.88 | CRBN (0.57) | CRBNDDB1GSPT1POLB | |
| SCHEMBL30828444 | 0.88 | CRBN (0.55) | CRBNDDB1GSPT1POLB | |
| SCHEMBL25207570 | 0.85 | CRBN (0.48) | CRBNDDB1GSPT1POLB | |
| SCHEMBL31579518 | 0.84 | CRBN (0.60) | CRBNDDB1GSPT1POLB | |
| SCHEMBL30828417 | 0.83 | CRBN (0.64) | CRBNDDB1GSPT1POLB | |
| Hydrochloric Acid SCHEMBL30828451 | 0.82 | CRBN (0.62) | CRBNDDB1GSPT1POLB | |
| SCHEMBL24819657 | 0.82 | ALDH1A1 (0.51) | CRBNDDB1GSPT1POLB | |
| Hydrochloric Acid SCHEMBL30938121 | 0.82 | CRBN (0.50) | CRBNDDB1GSPT1POLB | |
| Hydrochloric Acid SCHEMBL30938132 | 0.81 | CRBN (0.49) | CRBNDDB1GSPT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561249-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 细胞基因公司 | 2024-02-13 | — | — | CN | disclosed |