SCHEMBL315803

SCHEMBL315803

Cc1c(CCl)cc(C(=O)O)c(C)c1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HMGB1 P09429 2/20 0.33
CXCL12 P48061 2/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
NOTUM Q6P988 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CSNK2A1 P68400 1/20 0.32
CYP3A4 P08684 1/20 0.32
ACHE P22303 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.32
PON1 P27169 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27534516 0.85 KDM4E (0.41) KDM4EKMT2AMEN1TDP1HMGB1
SCHEMBL20141358 0.85 KDM4E (0.41) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL316590 0.83 KDM4E (0.40) KDM4EKMT2AMEN1TDP1HMGB1
SCHEMBL14989153 0.80 KDM4E (0.50) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL27400020 0.78 TPMT (0.42) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL27535391 0.78 CYP1A2 (0.37) KDM4EKMT2ASMN1; SMN2NOTUMMRGPRX4
SCHEMBL7954657 0.78 KDM4E (0.35) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL26683198 0.78 HPGD (0.41) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL27558948 0.75 MEN1 (0.42) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL27770817 0.74 KDM4E (0.39) KDM4EKMT2AMEN1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1911814-B2 Methods for preparing curable pigment inkjet ink sets AGFA NV (BE) 2023-07-12 EP disclosed
EP-2740773-B1 Curable pigment inkjet ink sets and methods for preparing the said ink sets AGFA NV (BE) 2018-12-12 EP disclosed
EP-2801594-B1 Methods for preparing curable pigment inkjet ink sets AGFA GRAPHICS NV (BE) 2017-06-28 EP disclosed
EP-1911814-B1 Methods for preparing curable pigment inkjet ink sets AGFA GRAPHICS NV (BE) 2015-07-29 EP disclosed
EP-2801594-A2 Methods for preparing curable pigment inkjet ink sets AGFA GRAPHICS NV (BE) 2014-11-12 EP disclosed
EP-2740773-A1 Curable pigment inkjet ink sets and methods for preparing the said ink sets AGFA GRAPHICS NV (BE) 2014-06-11 EP disclosed
EP-1966330-B1 NON-AQUEOUS PIGMENT DISPERSIONS USING DISPERSION SYNERGISTS AGFA GRAPHICS NV (BE) 2013-03-13 EP disclosed
EP-1960478-B1 NON-AQUEOUS INKJET INKS OF QUINACRIDONE MIXED CRYSTAL PIGMENTS AGFA GRAPHICS NV (BE) 2012-11-14 EP disclosed
US-8197584-B2 Methods for preparing curable pigment inkjet ink sets AGFA GRAPHICS NV (BE) 2012-06-12 US disclosed
US-8138238-B2 Non-aqueous pigmented inkjet inks AGFA GRAPHICS NV (BE) 2012-03-20 US disclosed
WO-2008043677-A1 NON-AQUEOUS PIGMENTED INKJET INKS AGFA GRAPHICS NV (BE) 2008-04-17 WO disclosed
WO-2008043696-A1 NON-AQUEOUS PIGMENTED INKJET INKS AGFA GRAPHICS NV (BE) 2008-04-17 WO disclosed
WO-2008043681-A1 NON-AQUEOUS PIGMENTED INKJET INKS AGFA GRAPHICS NV (BE) 2008-04-17 WO disclosed
EP-1911816-A1 Non-aqueous pigmented inkjet inks Agfa Graphics N.V. (BE) 2008-04-16 EP disclosed
EP-1911814-A1 Methods for preparing curable pigment inkjet ink sets Agfa Graphics N.V. (BE) 2008-04-16 EP disclosed
EP-1911813-A1 Non-aqueous pigmented inkjet inks Agfa Graphics N.V. (BE) 2008-04-16 EP disclosed
EP-1911815-A1 Non-aqueous pigmented inkjet inks Agfa Graphics N.V. (BE) 2008-04-16 EP disclosed
WO-2007060259-A2 NON-AQUEOUS PIGMENT DISPERSIONS USING DISPERSION SYNERGISTS AGFA GRAPHICS NV (BE) 2007-05-31 WO disclosed
WO-2007060254-A2 QUINACRIDONE DERIVATIVES AS DISPERSION SYNERGISTS AGFA GRAPHICS NV (BE) 2007-05-31 WO disclosed
WO-2007060258-A2 NON-AQUEOUS INKJET INKS OF QUINACRIDONE MIXED CRYSTAL PIGMENTS AGFA GRAPHICS NV (BE) 2007-05-31 WO disclosed