Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | PON1 | P27169 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141358 | 0.81 | KDM4E (0.41) | KDM4EMEN1KMT2ATDP1HMGB1 | |
| SCHEMBL315803 | 0.78 | KDM4E (0.39) | KDM4EMEN1KMT2ATDP1HMGB1 | |
| SCHEMBL27415299 | 0.76 | KDM4E (0.48) | KDM4EKMT2AHMGB1CXCL12ALDH1A1 | |
| SCHEMBL26683198 | 0.74 | HPGD (0.41) | KDM4EMEN1KMT2ATDP1HMGB1 | |
| SCHEMBL27400020 | 0.74 | TPMT (0.42) | KDM4EMEN1KMT2ATDP1HMGB1 | |
| SCHEMBL7959176 | 0.73 | NPSR1 (0.44) | KDM4EHMGB1CXCL12HPGDHSD17B10 | |
| SCHEMBL20140124 | 0.73 | NPSR1 (0.39) | KDM4EHMGB1CXCL12HPGDHSD17B10 | |
| SCHEMBL27953149 | 0.73 | PON1 (0.32) | KMT2APON1 | |
| SCHEMBL7952596 | 0.72 | TPMT (0.48) | KDM4EMEN1KMT2ATDP1HPGD | |
| SCHEMBL27916175 | 0.72 | TPMT (0.39) | KDM4EMEN1KMT2ATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001083420-A2 | METHOD OF MAKING SUBSTITUTED DIHALO AROMATIC ACID CHLORIDES | OCCIDENTAL CHEMICAL CORPORATION (US) | 2001-11-08 | — | — | WO | claimed |
| WO-2001083420-A2 | METHOD OF MAKING SUBSTITUTED DIHALO AROMATIC ACID CHLORIDES | OCCIDENTAL CHEMICAL CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |