Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 17/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31581037 | 1.00 | KDR (0.45) | KDRCCNCCDK8KDM1AFLT3 | |
| SCHEMBL31580699 | 1.00 | KDR (0.45) | KDRCCNCCDK8KDM1AFLT3 | |
| SCHEMBL31580341 | 0.91 | PDK2 (0.43) | CCNCCDK8 | |
| SCHEMBL31580365 | 0.91 | PDK2 (0.43) | CCNCCDK8 | |
| SCHEMBL31580625 | 0.91 | PDK2 (0.43) | CCNCCDK8 | |
| SCHEMBL31580729 | 0.88 | PDK2 (0.45) | CCNCCDK8KDM1A | |
| SCHEMBL31580921 | 0.88 | PDK2 (0.45) | CCNCCDK8KDM1A | |
| SCHEMBL31580581 | 0.88 | PDK2 (0.45) | CCNCCDK8KDM1A | |
| SCHEMBL31580423 | 0.88 | PDK2 (0.45) | CCNCCDK8KDM1A | |
| SCHEMBL31580766 | 0.87 | HPGD (0.43) | FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106722-A1 | INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2025-05-22 | — | — | WO | claimed |
| WO-2025106722-A1 | INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2025-05-22 | — | — | WO | disclosed |