Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 10/20 | 0.38 |
| ▸ | CCND1 | P24385 | 10/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | BCR | P11274 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31580766 | 0.88 | HPGD (0.43) | MGLLACACBACACAHPGD | |
| SCHEMBL31580561 | 0.88 | TLR8 (0.41) | CDK4MGLLACACBACACAABL1 | |
| SCHEMBL31581091 | 0.87 | HPGD (0.44) | ACACBACACAHPGD | |
| SCHEMBL31580288 | 0.86 | FLT3 (0.46) | CDK4MGLLABL1BCR | |
| SCHEMBL31580625 | 0.83 | PDK2 (0.43) | HPGD | |
| SCHEMBL31580779 | 0.83 | FLT3 (0.44) | CDK4ACACBACACAABL1BCR | |
| SCHEMBL31580341 | 0.83 | PDK2 (0.43) | HPGD | |
| SCHEMBL31580409 | 0.83 | KDR (0.45) | — | |
| SCHEMBL31580699 | 0.83 | KDR (0.45) | — | |
| SCHEMBL31581040 | 0.83 | CCNC (0.36) | MGLLACACBACACAABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106722-A1 | INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2025-05-22 | — | — | WO | claimed |
| WO-2025106722-A1 | INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2025-05-22 | — | — | WO | disclosed |