SCHEMBL3158160

SCHEMBL3158160

C=C(C)C(=O)OCCC[SiH](OC)OCC

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.51
THRB P10828 1/20 0.49
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139125 0.92 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL136943 0.89 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL98029 0.87 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6765015 0.86 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19409171 0.86 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29432640 0.86 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16286969 0.86 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19409198 0.86 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8188279 0.85 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35127 0.83 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1702964-B1 HEAT RESISTANCE LUBRICITY IMPARTING COATING AGENT AND THERMAL TRANSFER RECORDING MEDIUM NATOCO CO LTD (JP) 2010-03-31 EP disclosed
CN-100558837-C Heat-resistant lubricity imparting coating agent and thermal transfer recording medium NATOCO CO LTD (JP) 2009-11-11 CN disclosed
US-20070082147-A1 Heat-resistant lubricity imparting coating agent, and thermal transfer recording medium NATOCO CO., LTD. (JP) 2007-04-12 US disclosed
CN-1914286-A Heat resistance lubricity imparting coating agent and thermal transfer recording medium NATOCO CO LTD (JP) 2007-02-14 CN disclosed
EP-1702964-A1 HEAT RESISTANCE LUBRICITY IMPARTING COATING AGENT AND THERMAL TRANSFER RECORDING MEDIUM Natoco Co., Ltd. (JP) 2006-09-20 EP disclosed
EP-0978541-B1 POLYMER MIXTURE USEFUL FOR THE PRODUCTION OF AN ANTI-STICKING AGENT AND A HEAT SENSITIVE TRANSFER RECORDING FILM NATOCO PAINT KK (JP) 2004-06-23 EP disclosed
US-6440572-B1 POLYDIMETHYLSILOXANE BLOCK TYPE COPOLYMER AND RESIN(S) SELECTED FROM: POLYVINYL ACETATES, POLYAMIDE, ACRYLIC RESIN, EPOXY RESIN, UNSATURATED POLYESTER RESIN AND PRECURSOR OF UNSATURATED POLYESTER AND/OR CELLULOSE DERIVATIVES NATOCO PAINT CO., LTD. (JP) 2002-08-27 US disclosed
EP-0978541-A1 NOVEL COMPOSITION, ANTISTICKING AGENTS, AND THERMAL TRANSFER RECORDING FILMS Natoco Paint Co., Ltd. (JP) 2000-02-09 EP disclosed
US-5834396-A THE DYE-CONTAINING LAYER/SUBSTRATE HAVING A HEAT- AND FRICTION-RESISTANT TOP LAYER; ANTISOILANTS AND -STICKING AGENTS; RESOLUTION; PRINTERS AND COPIERS USING AN N-TIMES SPEED MODE; STORAGE STABILITY RICOH COMPANY, LTD. (JP) 1998-11-10 US disclosed