Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139125 | 0.91 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3158160 | 0.86 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL98029 | 0.86 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19409198 | 0.84 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16286969 | 0.84 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29432640 | 0.84 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19409171 | 0.84 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5164067 | 0.81 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15161889 | 0.81 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL143882 | 0.80 | THRB (0.56) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6830816-B2 | For preparing lacquer | DEGUSSA AG (DE) | 2004-12-14 | — | — | US | claimed |
| US-20030008974-A1 | Highly filled, pasty, composition containing silicoorganic nanohybrid and/or microhybrid capsules for scratch-resistant and/or abrasion-resistant coatings | DEGUSSA AG (DE) | 2003-01-09 | — | — | US | claimed |
| EP-1249470-A2 | Highly filled pasty siliconorganic nano and/or microhybridcapsules containing composition for scratch and/or abrasion resistant coatings | Degussa AG (DE) | 2002-10-16 | — | — | EP | claimed |
| US-6830816-B2 | For preparing lacquer | DEGUSSA AG (DE) | 2004-12-14 | — | — | US | disclosed |
| US-20030008974-A1 | Highly filled, pasty, composition containing silicoorganic nanohybrid and/or microhybrid capsules for scratch-resistant and/or abrasion-resistant coatings | DEGUSSA AG (DE) | 2003-01-09 | — | — | US | disclosed |