Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25746145 | 0.85 | GAA (0.55) | CYP2C19ALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL18610932 | 0.77 | MEN1 (0.42) | ALDH1A1POLBKDM4EGAAHPGD | |
| SCHEMBL19208795 | 0.75 | ELANE (0.49) | CYP2C19ALDH1A1SMN1; SMN2GAAMAPK8 | |
| SCHEMBL16709542 | 0.75 | TSPO (0.53) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HPGD | |
| SCHEMBL24076897 | 0.74 | GAA (0.55) | CYP2C19ALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL11631485 | 0.74 | MAPK1 (0.49) | CYP2C19ALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL19234362 | 0.73 | ELANE (0.43) | CYP2C19ALDH1A1SMN1; SMN2GAAMAPK8 | |
| SCHEMBL24076251 | 0.73 | GAA (0.51) | CYP2C19ALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL14564344 | 0.73 | BRD4 (0.49) | CYP2C19ALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL13653124 | 0.73 | MEN1 (0.50) | CYP2C19ALDH1A1POLBKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106383-A1 | PYRROLIDINYL DERIVATIVES USEFUL AS HCN1/HCN 2 MODULATORS | MERCK SHARP & DOHME LLC (US) | 2025-05-22 | — | — | WO | disclosed |