⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231283 | 0.93 | — | — | |
| SCHEMBL2325814 | 0.93 | — | — | |
| SCHEMBL8493091 | 0.90 | NISCH (0.32) | — | |
| SCHEMBL5160972 | 0.90 | KMT2A (0.31) | — | |
| SCHEMBL7534899 | 0.90 | NISCH (0.32) | — | |
| SCHEMBL5057236 | 0.90 | KMT2A (0.31) | — | |
| SCHEMBL435761 | 0.90 | NISCH (0.32) | — | |
| SCHEMBL2044612 | 0.89 | — | — | |
| SCHEMBL78897 | 0.89 | — | — | |
| SCHEMBL149012 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874353-B | Microbiocidal derivatives | 先正达农作物保护股份公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118063435-A | Piperidine-2, 6-dione derivative and application thereof | 西藏海思科制药有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117720517-A | AR inhibitor, composition thereof and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-03-19 | — | — | CN | claimed |
| WO-2023208165-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2023-11-02 | — | — | WO | claimed |
| WO-2023202687-A1 | PYRAZINONE DERIVATIVE AND USE THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2023-10-26 | — | — | WO | claimed |
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | claimed |
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | claimed |
| CN-115916747-A | Fused heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-04-04 | — | — | CN | claimed |
| US-20220272976-A1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-09-01 | — | — | US | claimed |
| CN-114805303-A | Molecule with double functions of degrading EGFR (epidermal growth factor receptor), composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114507235-A | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-114437035-A | Compound for inhibiting and degrading IRAK4, pharmaceutical composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114057733-A | Fused heterocyclic derivative and application thereof in medicine | 海思科医药集团股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-113999233-A | BTK inhibitor ring derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-113874353-A | Microbicidal derivatives | 先正达农作物保护股份公司 | 2021-12-31 | — | — | CN | claimed |
| CN-113544130-A | BTK inhibitor ring derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-112812100-A | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-112390785-A | BET family bromodomain inhibitor ring derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-02-23 | — | — | CN | claimed |
| WO-2020239856-A1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-12-03 | — | — | WO | claimed |
| CN-112010858-A | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2020-12-01 | — | — | CN | claimed |