SCHEMBL31586460

SCHEMBL31586460

O=C(O)CN1CCN(c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)CC1

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 12/20 0.61
▸ ESR1 P03372 1/20 0.57
▸ CSNK1A1 P48729 2/20 0.55
▸ IKZF1 Q13422 1/20 0.52
▸ IKZF2 Q9UKS7 6/20 0.52
▸ WIZ O95785 1/20 0.51
▸ GSPT1 P15170 1/20 0.49
▸ DDB1 Q16531 1/20 0.49
▸ IKZF3 Q9UKT9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24207552 1.00 CRBN (0.61) CRBNESR1CSNK1A1IKZF1IKZF2
SCHEMBL30906253 0.94 CRBN (0.63) CRBNESR1CSNK1A1IKZF1IKZF2
SCHEMBL30889713 0.93 CRBN (0.57) CRBNESR1CSNK1A1IKZF1IKZF2
SCHEMBL30906266 0.92 CRBN (0.55) CRBNESR1CSNK1A1IKZF1IKZF2
SCHEMBL30822468 0.92 CRBN (0.61) CRBNESR1CSNK1A1GSPT1IKZF3
SCHEMBL31586284 0.92 CRBN (0.58) CRBNESR1CSNK1A1IKZF1IKZF2
SCHEMBL31586767 0.90 CRBN (0.56) CRBNESR1CSNK1A1IKZF1IKZF2
SCHEMBL24734973 0.90 CRBN (0.56) CRBNESR1CSNK1A1IKZF1IKZF2
SCHEMBL24734976 0.89 CRBN (0.55) CRBNESR1CSNK1A1IKZF1IKZF2
SCHEMBL30822469 0.89 CRBN (0.55) CRBNESR1CSNK1A1IKZF1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025103502-A1 COMPOUNDS AND METHODS OF TREATING CANCERS CULLGEN INC. (US) 2025-05-22 — — WO disclosed
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