Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.50 |
| ▸ | CDK9 | P50750 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | CLK3 | P49761 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12912282 | 0.79 | CDK9 (0.53) | DYRK1ACDK9KDM4EALDH1A1LMNA | |
| SCHEMBL12891208 | 0.77 | DYRK1A (0.47) | DYRK1ACDK9KDM4EALDH1A1LMNA | |
| SCHEMBL18335769 | 0.74 | PARG (0.39) | DYRK1ACDK9KDM4EALDH1A1LMNA | |
| SCHEMBL20508610 | 0.74 | DYRK1A (0.58) | DYRK1ACDK9ALDH1A1DYRK2MAPT | |
| SCHEMBL20508457 | 0.73 | DYRK1A (0.56) | DYRK1ACDK9KDM4EALDH1A1DYRK2 | |
| SCHEMBL20508516 | 0.72 | CDK9 (0.40) | DYRK1ACDK9DYRK2CSNK1ECLK1 | |
| SCHEMBL31721265 | 0.71 | CDK9 (0.45) | DYRK1ACDK9KDM4EALDH1A1LMNA | |
| SCHEMBL20508498 | 0.70 | CNR2 (0.41) | DYRK1ACDK9DYRK2 | |
| SCHEMBL20449069 | 0.70 | DYRK1A (0.47) | DYRK1ACDK9LMNADYRK2MAPT | |
| SCHEMBL30917272 | 0.69 | CDK9 (0.48) | DYRK1ACDK9KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106949-A1 | WRN INHIBITORS | RADD PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |