Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 12/20 | 0.36 |
| ▸ | CDK2 | P24941 | 12/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.32 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.32 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587757 | 0.90 | CCNE1 (0.35) | CCNE1CDK2GSK3BSHMT1SHMT2 | |
| SCHEMBL31587151 | 0.84 | CDK2 (0.50) | CCNE1CDK2GSK3B | |
| SCHEMBL31586737 | 0.84 | AR (0.35) | CCNE1CDK2ARGSK3BCRACR2A | |
| SCHEMBL31587991 | 0.84 | CRACR2A (0.38) | CCNE1CDK2ARGSK3BCRACR2A | |
| SCHEMBL31587731 | 0.83 | CCNE1 (0.39) | CCNE1CDK2GSK3BSHMT1SHMT2 | |
| SCHEMBL31587153 | 0.82 | CDK2 (0.36) | CCNE1CDK2ARGSK3BCTPS1 | |
| SCHEMBL31587604 | 0.81 | CCNE1 (0.36) | CCNE1CDK2ARGSK3BCRACR2A | |
| SCHEMBL31587062 | 0.80 | CDK2 (0.37) | CCNE1CDK2ARGSK3BCRACR2A | |
| SCHEMBL31587266 | 0.80 | CDK2 (0.34) | CCNE1CDK2ARGSK3BCRACR2A | |
| SCHEMBL31586967 | 0.80 | KCNJ6 (0.41) | CCNE1CDK2ARCTPS1CRACR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104236-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-05-22 | — | — | WO | claimed |
| WO-2025104236-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-05-22 | — | — | WO | disclosed |