Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 14/20 | 0.35 |
| ▸ | CDK2 | P24941 | 14/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587015 | 0.90 | CCNE1 (0.36) | CCNE1CDK2GSK3BSHMT1SHMT2 | |
| SCHEMBL31587731 | 0.85 | CCNE1 (0.39) | CCNE1CDK2KCNJ6KCNJ3GSK3B | |
| SCHEMBL31587155 | 0.84 | CDK2 (0.50) | CCNE1CDK2GSK3B | |
| SCHEMBL31587604 | 0.84 | CCNE1 (0.36) | CCNE1CDK2GSK3BNPC1RAB9A | |
| SCHEMBL31587991 | 0.83 | CRACR2A (0.38) | CCNE1CDK2GSK3BGLS | |
| SCHEMBL31587181 | 0.83 | CDK2 (0.38) | CCNE1CDK2KCNJ6KCNJ3GSK3B | |
| SCHEMBL31517548 | 0.82 | CCNE1 (0.36) | CCNE1CDK2GSK3BNPC1RAB9A | |
| SCHEMBL31586737 | 0.81 | AR (0.35) | CCNE1CDK2GSK3BGLS | |
| SCHEMBL31587666 | 0.80 | CDK2 (0.40) | CCNE1CDK2KCNJ6KCNJ3 | |
| SCHEMBL31587062 | 0.80 | CDK2 (0.37) | CCNE1CDK2GSK3BGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104236-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-05-22 | — | — | WO | claimed |
| WO-2025104236-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-05-22 | — | — | WO | disclosed |