SCHEMBL31587724

SCHEMBL31587724

COC(=O)/C(=C/N(C)C)C(=O)C1CC1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1015828 1.00 MAPT (0.36) MAPTKDM4EMEN1GAAKMT2A
SCHEMBL1015830 1.00 MAPT (0.36) MAPTKDM4EMEN1GAAKMT2A
SCHEMBL1014891 0.93 MAPT (0.35) MAPT
SCHEMBL1016151 0.93 CES2 (0.39) MAPT
SCHEMBL1016150 0.93 CES2 (0.39) MAPT
SCHEMBL1014889 0.93 MAPT (0.35) MAPT
SCHEMBL1014910 0.91 CES2 (0.42) MAPT
SCHEMBL1014911 0.91 CES2 (0.42) MAPT
SCHEMBL21960394 0.89 RECQL (0.39) MAPTRECQL
SCHEMBL1015324 0.82 MAPT (0.33) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025105858-A1 HETEROARYL-DERIVATIVE COMPOUND AND USE THEREOF (주)신테카바이오 2025-05-22 WO disclosed