Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.43 |
| ▸ | GRM5 | P41594 | 11/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31589298 | 1.00 | GRM1 (0.43) | GRM1GRM5NR1H2GPR119PDK4 | |
| SCHEMBL31590064 | 0.89 | GRM1 (0.56) | GRM1GRM5GPR119PDK4NAMPT | |
| SCHEMBL31589689 | 0.89 | NR1H2 (0.46) | GRM1GRM5NR1H2GPR119 | |
| SCHEMBL3466461 | 0.83 | PDK4 (0.44) | GRM1GRM5NR1H2GPR119PDK4 | |
| SCHEMBL29220909 | 0.83 | GPR119 (0.54) | GRM1GRM5NR1H2GPR119PDK4 | |
| SCHEMBL18352271 | 0.82 | GRM1 (0.45) | GRM1GRM5NR1H2PDK4NAMPT | |
| SCHEMBL29351210 | 0.82 | GRM1 (0.45) | GRM1GRM5NR1H2PDK4NAMPT | |
| SCHEMBL31589212 | 0.81 | GPR119 (0.41) | GRM1GRM5NR1H2GPR119PDK4 | |
| SCHEMBL31598628 | 0.81 | GPR119 (0.41) | GRM1GRM5NR1H2GPR119PDK4 | |
| SCHEMBL24793344 | 0.81 | GRM1 (0.39) | GRM1GRM5NR1H2GPR119PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025110780-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS DNA POLYMERASE THETA INHIBITORS FOR THE PREVENTION OR TREATMENT OF CANCER | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2025-05-30 | — | — | WO | disclosed |
| CN-120040437-A | Novel heterocyclic compound and pharmaceutical composition comprising same | 株式会社大熊制药 | 2025-05-27 | — | — | CN | disclosed |