Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | TNNI3K | Q59H18 | 4/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591338 | 0.87 | TEAD1 (0.49) | TEAD1YAP1TLR2TLR1SCN9A | |
| SCHEMBL27255220 | 0.87 | TEAD1 (0.49) | TEAD1YAP1TLR2TLR1SCN9A | |
| SCHEMBL27255265 | 0.83 | TEAD1 (0.49) | TEAD1YAP1TLR2TLR1SCN9A | |
| SCHEMBL27255195 | 0.82 | TEAD1 (0.64) | TEAD1YAP1TLR2TLR1SCN9A | |
| SCHEMBL30839909 | 0.81 | TEAD1 (0.49) | TEAD1YAP1TLR2TLR1SCN9A | |
| SCHEMBL27255427 | 0.81 | TEAD1 (0.49) | TEAD1YAP1TLR2TLR1SCN9A | |
| SCHEMBL27255547 | 0.78 | TEAD1 (0.49) | TEAD1YAP1TLR2TLR1SCN9A | |
| SCHEMBL27255360 | 0.78 | TEAD1 (0.48) | TEAD1YAP1TLR2TLR1SCN9A | |
| SCHEMBL27255432 | 0.78 | TEAD1 (0.48) | TEAD1YAP1TLR2TLR1SCN9A | |
| SCHEMBL27255231 | 0.77 | TEAD1 (0.46) | TEAD1YAP1SCN9ATNNI3KMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120051465-A | Novel heterobicyclic compounds for inhibiting YAP-TEAD interactions and pharmaceutical compositions containing the same | 韩美药品株式会社 | 2025-05-27 | — | — | CN | disclosed |