Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.41 |
| ▸ | TNKS | O95271 | 5/20 | 0.41 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | GUSB | P08236 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8278866 | 0.70 | PARP1 (0.46) | TNKS2PARP1NPC1RAB9APOLB | |
| SCHEMBL31591432 | 0.69 | NPC1 (0.50) | TNKS2TNKSPARP1GUSBNPC1 | |
| SCHEMBL7965710 | 0.68 | PDE5A (0.69) | GUSBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29589542 | 0.67 | CYP1A2 (0.41) | NPC1RAB9AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL27091284 | 0.67 | CYP1A2 (0.41) | NPC1RAB9AL3MBTL1MAPTALDH1A1 | |
| Oxypurinol SCHEMBL8258215 | 0.67 | PARP1 (0.38) | TNKS2TNKSPARP1GUSBALDH1A1 | |
| SCHEMBL6695759 | 0.61 | TNKS2 (0.81) | TNKS2TNKSPARP1GUSBNPC1 | |
| SCHEMBL11011451 | 0.61 | MAPT (0.59) | L3MBTL1MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL8621956 | 0.60 | PARP1 (0.96) | TNKS2TNKSPARP1NPC1RAB9A | |
| SCHEMBL30616953 | 0.60 | AKT2 (0.48) | L3MBTL1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4559520-A1 | NOVEL AQP4 INHIBITORS | Origenis GmbH (DE) | 2025-05-28 | — | — | EP | claimed |
| EP-4559520-A1 | NOVEL AQP4 INHIBITORS | Origenis GmbH (DE) | 2025-05-28 | — | — | EP | disclosed |