Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 4/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965710 | 0.73 | PDE5A (0.69) | GUSBKDM4EHPGDPDE5AALDH1A1 | |
| Oxypurinol SCHEMBL8258215 | 0.70 | PARP1 (0.38) | GUSBKDM4EHPGDALDH1A1CYP1A2 | |
| SCHEMBL31591419 | 0.69 | TNKS2 (0.41) | NPC1RAB9AGUSBKDM4EHPGD | |
| SCHEMBL29941421 | 0.67 | NPC1 (1.00) | NPC1GBA1RAB9AATMERAP1 | |
| SCHEMBL15190213 | 0.67 | NPC1 (1.00) | NPC1GBA1RAB9AATMERAP1 | |
| SCHEMBL8278866 | 0.66 | PARP1 (0.46) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL19236510 | 0.66 | CYP1A2 (0.49) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL2101505 | 0.66 | AURKA (0.56) | NPC1GBA1RAB9AATMERAP1 | |
| SCHEMBL9117502 | 0.63 | NPC1 (0.54) | NPC1GBA1RAB9AATMERAP1 | |
| SCHEMBL7700240 | 0.63 | NPC1 (0.42) | NPC1GBA1RAB9AATMERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4559520-A1 | NOVEL AQP4 INHIBITORS | Origenis GmbH (DE) | 2025-05-28 | — | — | EP | claimed |
| EP-4559520-A1 | NOVEL AQP4 INHIBITORS | Origenis GmbH (DE) | 2025-05-28 | — | — | EP | disclosed |