Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | APP | P05067 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22389483 | 0.83 | RORC (0.72) | RORCTP53MAPTGAANPC1 | |
| SCHEMBL31591973 | 0.78 | RORC (0.59) | RORCCCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL24185770 | 0.77 | RORC (1.00) | RORCTP53MAPTGAANPC1 | |
| SCHEMBL12422075 | 0.74 | RORC (0.56) | RORCTP53MAPTGAANPC1 | |
| SCHEMBL22390561 | 0.74 | MAPT (0.62) | RORCTP53MAPTGAANPC1 | |
| SCHEMBL1988015 | 0.74 | APP (0.69) | TP53MAPTGAANPC1RAB9A | |
| SCHEMBL31591976 | 0.73 | CCNE1 (0.51) | RORCTP53CCNE1CDK2CDK5 | |
| SCHEMBL12421992 | 0.72 | TP53 (0.66) | RORCTP53MAPTGAANPC1 | |
| SCHEMBL24185845 | 0.72 | RORC (0.67) | RORCTP53MAPTGAANPC1 | |
| SCHEMBL2091539 | 0.71 | RORC (0.57) | RORCTP53MAPTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912563-B | Benzo five-membered nitrogen heterocyclic compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2025-05-27 | — | — | CN | disclosed |