Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 11/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.38 |
| ▸ | SMOX | Q9NWM0 | 2/20 | 0.37 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31594090 | 0.94 | CXCR2 (0.43) | CXCR2CXCR1KDM1ARCOR1POLB | |
| SCHEMBL31594638 | 0.94 | CXCR2 (0.43) | CXCR2CXCR1KDM1ARCOR1SMOX | |
| SCHEMBL31594557 | 0.93 | CXCR2 (0.43) | CXCR2CXCR1KDM1ARCOR1CYP2C9 | |
| SCHEMBL31594364 | 0.91 | CXCR2 (0.46) | CXCR2CXCR1CYP2C9LMNAPOLB | |
| SCHEMBL31594554 | 0.91 | CXCR2 (0.46) | CXCR2CXCR1KDM1ARCOR1SMOX | |
| SCHEMBL31594096 | 0.90 | CXCR2 (0.45) | CXCR2CXCR1CYP2C9 | |
| SCHEMBL31594321 | 0.90 | CXCR2 (0.41) | CXCR2CXCR1CYP2C9 | |
| SCHEMBL31594124 | 0.89 | CXCR2 (0.44) | CXCR2CXCR1CYP2C9LMNAMAPK14 | |
| SCHEMBL31594646 | 0.89 | CXCR2 (0.47) | CXCR2CXCR1CYP2C9LMNACA12 | |
| SCHEMBL31594625 | 0.88 | CXCR2 (0.43) | CXCR2CXCR1LMNAMAPTMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250170141-A1 | MRGPRX2 MODULATORS AND RELATED METHODS OF TREATMENT | INCYTE CORPORATION | 2025-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250170141-A1 | MRGPRX2 MODULATORS AND RELATED METHODS OF TREATMENT | MRGPRX2, MRGPRX1, MRGPRX4 | CXCR2 763/4885CXCR1 1016/4885KDM1A 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.