⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164284 | 0.79 | — | — | |
| SCHEMBL11002111 | 0.79 | — | — | |
| SCHEMBL29210021 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL14655349 | 0.73 | — | — | |
| SCHEMBL11122193 | 0.71 | — | — | |
| SCHEMBL1940539 | 0.71 | — | — | |
| Methyl Alcohol SCHEMBL14759248 | 0.69 | — | — | |
| SCHEMBL7925304 | 0.69 | — | — | |
| Trichloroethane SCHEMBL28866673 | 0.69 | — | — | |
| SCHEMBL1445681 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074501-B | Process for preparing 2-chloroacetoacetamide and 2-chloroacetoacetate | 阿尔萨达股份公司 | 2022-03-29 | — | — | CN | disclosed |
| EP-3762359-B1 | METHOD FOR PREPARATION OF 2-CHLOROACETOACETIC ACID AMIDE AND ESTER | ARXADA AG (CH) | 2022-02-23 | — | — | EP | disclosed |
| US-10934252-B1 | Method for preparation of 2-chloroacetoacetic acid amide and ester | LONZA SOLUTIONS AG (CH) | 2021-03-02 | — | — | US | disclosed |
| US-20210047263-A1 | Method for Preparation of 2-Chloroacetoacetic Acid Amide and Ester | ARXADA AG (CH) | 2021-02-18 | — | — | US | disclosed |
| EP-3762359-A1 | METHOD FOR PREPARATION OF 2-CHLOROACETOACETIC ACID AMIDE AND ESTER | Lonza Solutions AG (CH) | 2021-01-13 | — | — | EP | disclosed |
| CN-112074501-A | Process for preparing 2-chloroacetoacetamide and 2-chloroacetoacetate | 隆萨解决方案股份公司 | 2020-12-11 | — | — | CN | disclosed |
| WO-2019170791-A1 | METHOD FOR PREPARATION OF 2-CHLOROACETOACETIC ACID AMIDE AND ESTER | LONZA LTD (CH) | 2019-09-12 | — | — | WO | disclosed |
| CN-101061090-B | Preparation method of alpha, alpha-difluoroamine | HOKKAIDO UNIV NAT UNIVERSITY CORP | 2011-06-15 | — | — | CN | disclosed |
| EP-1923379-B1 | Process for preparing chlorinated carbonyl compounds in jet loop reactors | WACKER CHEMIE AG (DE) | 2010-03-03 | — | — | EP | disclosed |
| US-7476772-B2 | Process for preparing chlorinated carbonyl compounds in jet loop reactors | WACKER CHEMIE AG (DE) | 2009-01-13 | — | — | US | disclosed |
| EP-1923379-A1 | Process for preparing chlorinated carbonyl compounds in jet loop reactors | Wacker Chemie AG (DE) | 2008-05-21 | — | — | EP | disclosed |
| US-20080114196-A1 | Process For Preparing Chlorinated Carbonyl Compounds In Jet Loop Reactors | WACKER CHEMIE AG (DE) | 2008-05-15 | — | — | US | disclosed |
| CN-101061090-A | Preparation method of alpha, alpha-difluoroamine | UNIV HOKKAIDO NAT UNIV CORP (JP) | 2007-10-24 | — | — | CN | disclosed |
| EP-0005849-B2 | PROCESS FOR PREPARING ALPHA-CHLORO-N-MONOALKYL-ACETOACETAMIDES | Wacker-Chemie GmbH (DE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0005849-B1 | PROCESS FOR PREPARING ALPHA-CHLORO-N-MONOALKYL-ACETOACETAMIDES | Wacker-Chemie GmbH (DE) | 1981-10-21 | — | — | EP | disclosed |
| US-4207259-A | WATER AS SOLVENT | WACKER-CHEMIE GMBH (DE) | 1980-06-10 | — | — | US | disclosed |
| EP-0005849-A1 | Process for preparing alpha-chloro-N-monoalkyl-acetoacetamides | Wacker-Chemie GmbH (DE) | 1979-12-12 | — | — | EP | disclosed |