Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599676 | 0.77 | LTA4H (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL24746627 | 0.77 | CYP2D6 (0.46) | USP2SMN1; SMN2MGLL | |
| SCHEMBL2323290 | 0.76 | USP2 (0.50) | USP2SMN1; SMN2DPP4CHRM2CHRM4 | |
| SCHEMBL18390217 | 0.75 | JAK3 (0.38) | USP2SMN1; SMN2GRIN2BGRIN2CJAK3 | |
| SCHEMBL31713803 | 0.75 | USP2 (0.36) | USP2SMN1; SMN2GRIN2BGRIN2CJAK3 | |
| SCHEMBL18497949 | 0.75 | CYP2D6 (0.43) | USP2SMN1; SMN2PARP1OPRM1OPRD1 | |
| SCHEMBL22230120 | 0.75 | TSHR (0.47) | USP2SMN1; SMN2PARP1 | |
| SCHEMBL14085918 | 0.74 | NPFFR1 (0.47) | USP2ALDH1A1MAPK1OPRD1OPRK1 | |
| SCHEMBL18704900 | 0.74 | HRH3 (0.40) | USP2SMN1; SMN2GRIN2BGRIN2CJAK3 | |
| SCHEMBL23994976 | 0.74 | JAK3 (0.39) | USP2SMN1; SMN2GRIN2BGRIN2CJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111251-A1 | COMPOUNDS THAT INHIBIT POLO-LIKE KINASE 4 | EXELIXIS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |