Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31600295 | 0.98 | MAPT (0.38) | MAPTALDH1A1KDM4ENSD2ADORA1 | |
| SCHEMBL31600817 | 0.82 | ADORA2A (0.38) | MAPTALDH1A1KDM4ENSD2ADORA1 | |
| Hydrochloric Acid SCHEMBL31600106 | 0.81 | ADORA2A (0.37) | MAPTALDH1A1KDM4ENSD2ADORA1 | |
| SCHEMBL31210876 | 0.79 | AXL (0.36) | MAPTALDH1A1KDM4ENSD2ADORA1 | |
| SCHEMBL31600644 | 0.77 | ALDH1A1 (0.42) | MAPTALDH1A1KDM4ENSD2ADORA1 | |
| Hydrochloric Acid SCHEMBL31600476 | 0.75 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ENSD2ADORA1 | |
| SCHEMBL2182645 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL18662690 | 0.71 | ADORA2A (0.36) | MAPTALDH1A1KDM4ENSD2ADORA1 | |
| Hydrochloric Acid SCHEMBL16714643 | 0.71 | ADORA2A (0.36) | MAPTALDH1A1KDM4ENSD2ADORA1 | |
| SCHEMBL20377846 | 0.70 | ALDH1A1 (0.37) | MAPTALDH1A1KDM4ENSD2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |