SCHEMBL31601548

SCHEMBL31601548

COc1ccc(CN2C(=O)CCC(n3c(=O)n(C)c4cc(N5CCC(C(OC)OC)CC5)ccc43)C2=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.44
▸ KMT2A Q03164 5/20 0.44
▸ LMNA P02545 2/20 0.43
▸ ALDH1A1 P00352 5/20 0.38
▸ DDB1 Q16531 2/20 0.36
▸ CRBN Q96SW2 2/20 0.36
▸ ADRA1D P25100 1/20 0.36
▸ ADRA1A P35348 1/20 0.36
▸ ADRA1B P35368 1/20 0.36
▸ PARG Q86W56 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ HPGD P15428 1/20 0.35
▸ BLM P54132 1/20 0.35
▸ MAPT P10636 3/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ TSHR P16473 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30139739 0.89 MEN1 (0.49) MEN1KMT2ALMNAALDH1A1DDB1
SCHEMBL31701224 0.88 MEN1 (0.46) MEN1KMT2ALMNAALDH1A1DDB1
SCHEMBL27208411 0.87 MEN1 (0.45) MEN1KMT2ALMNAALDH1A1DDB1
SCHEMBL30981542 0.85 MEN1 (0.47) MEN1KMT2ALMNAALDH1A1ADRA1D
SCHEMBL24847115 0.85 MEN1 (0.41) MEN1KMT2ALMNAALDH1A1DDB1
SCHEMBL30180150 0.85 MEN1 (0.41) MEN1KMT2ALMNAALDH1A1DDB1
SCHEMBL30180067 0.85 MEN1 (0.41) MEN1KMT2ALMNAALDH1A1DDB1
SCHEMBL24847964 0.85 MEN1 (0.41) MEN1KMT2ALMNAALDH1A1DDB1
SCHEMBL24847993 0.84 MEN1 (0.37) MEN1KMT2ALMNAALDH1A1POLB
SCHEMBL26447771 0.84 MEN1 (0.37) MEN1KMT2ALMNAALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025108411-A1 EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京沐华生物科技有限责任公司 2025-05-30 — — WO disclosed
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