Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27385858 | 0.80 | CDK8 (0.41) | DYRK1ACDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL27374115 | 0.76 | DYRK1A (0.38) | DYRK1ACDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL15688160 | 0.76 | CDK8 (0.45) | DYRK1ACDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL2673935 | 0.76 | DYRK1A (0.38) | DYRK1ACDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL25383486 | 0.72 | MC4R (0.38) | DYRK1ACDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL1154880 | 0.68 | CDK8 (0.41) | DYRK1ACDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL5572841 | 0.68 | CDK8 (0.41) | DYRK1ACDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL18319487 | 0.68 | DYRK1A (0.38) | DYRK1ACDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL21290406 | 0.67 | KDR (0.38) | DYRK1ACDK8ROCK1CHEK1MAP4K4 | |
| SCHEMBL19697361 | 0.67 | CDK8 (0.38) | DYRK1ACDK8ROCK1CHEK1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120077048-A | Tricyclic compounds and uses thereof | 诺华股份有限公司 | 2025-05-30 | — | — | CN | disclosed |