Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.44 |
| ▸ | SYK | P43405 | 3/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31602875 | 0.86 | HSD17B10 (0.41) | ARALDH1A1MAOBMAOAACHE | |
| SCHEMBL31602861 | 0.82 | KMT2A (0.48) | PDE1CMEN1KMT2AMAOBMAOA | |
| SCHEMBL31662257 | 0.82 | KMT2A (0.48) | PDE1CMEN1KMT2AMAOBMAOA | |
| SCHEMBL27273912 | 0.81 | AR (0.47) | ARSYKPDE1CMAOBMAOA | |
| SCHEMBL31169520 | 0.81 | AR (0.47) | ARSYKPDE1CMAOBMAOA | |
| SCHEMBL27273989 | 0.81 | MAOA (0.43) | ARSYKPDE1CMAOBMAOA | |
| SCHEMBL30987739 | 0.79 | KDM4E (0.44) | ARSYKPDE1CALDH1A1NOTUM | |
| SCHEMBL23070948 | 0.75 | CDC7 (0.38) | ARPDE1CALDH1A1POLBMEN1 | |
| SCHEMBL20562519 | 0.75 | ERCC1 (0.41) | ARPDE1CMAOBMAOAACHE | |
| SCHEMBL722949 | 0.73 | NOTUM (0.36) | ARPDE1CMAOBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111513-A1 | COMPOUNDS USEFUL IN THE MODULATION OF KLHDC1 AND KLHDC2 ACTIVITY | NURIX THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |