Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805088 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL29733282 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL17253548 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL14970051 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL30407095 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL1661549 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL30770739 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL14006989 | 0.72 | NCF1 (0.41) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL13668639 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL10049899 | 0.72 | PDE10A (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233493-A1 | Macrolides | Pfizer Products Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| EP-1836211-B1 | MACROLIDES | PFIZER PROD INC (US) | 2010-03-03 | — | — | EP | disclosed |