Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | THRB | P10828 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12415230 | 0.89 | MAPT (0.70) | MAPTKDM4ETHRBLMNANPSR1 | |
| SCHEMBL3166684 | 0.87 | MAPT (0.60) | MAPTKDM4ETHRBLMNANPSR1 | |
| SCHEMBL29715802 | 0.83 | MAPT (0.78) | MAPTKDM4ETHRBLMNANPSR1 | |
| SCHEMBL9866627 | 0.83 | MAPT (0.78) | MAPTKDM4ETHRBLMNANPSR1 | |
| SCHEMBL3164187 | 0.83 | MAPT (0.78) | MAPTKDM4ETHRBLMNANPSR1 | |
| SCHEMBL12415226 | 0.83 | MAPT (0.59) | MAPTKDM4ETHRBLMNANPSR1 | |
| SCHEMBL3154415 | 0.82 | MAPT (0.57) | MAPTKDM4ETHRBLMNANPSR1 | |
| SCHEMBL13809573 | 0.81 | MAPT (0.82) | MAPTKDM4ETHRBLMNANPSR1 | |
| SCHEMBL12415224 | 0.80 | MAPT (0.78) | MAPTKDM4ETHRBLMNANPSR1 | |
| SCHEMBL3166534 | 0.79 | MAPT (0.68) | MAPTKDM4ETHRBLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1498447-B1 | Photochromic material | PILOT INK CO LTD (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-7351362-B2 | Photochromic material | THE PILOT INK CO., LTD. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20050012081-A1 | Photochromic material | THE PILOT INK CO., LTD. | 2005-01-20 | — | — | US | disclosed |
| EP-1498447-A1 | Photochromic material | THE PILOT INK CO., LTD. (JP) | 2005-01-19 | — | — | EP | disclosed |