Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 6/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27139461 | 0.81 | MAPT (0.44) | ALDH1A1GAARPS6KA3PARP1 | |
| SCHEMBL27149694 | 0.80 | PLAT (0.39) | ALDH1A1RPS6KA3MAPKAPK2RPS6KA2CYP2D6 | |
| SCHEMBL27143039 | 0.78 | ALDH1A1 (0.42) | ALDH1A1GAARPS6KA3PARP1CYP2D6 | |
| SCHEMBL27142570 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GAARPS6KA3PARP1CYP2D6 | |
| SCHEMBL30241987 | 0.73 | ALDH1A1 (0.38) | ALDH1A1GAARPS6KA3CHEK1AURKA | |
| SCHEMBL30241989 | 0.73 | ALDH1A1 (0.38) | ALDH1A1GAARPS6KA3CHEK1AURKA | |
| SCHEMBL21798219 | 0.73 | KDM4E (0.38) | NOTUMALDH1A1GAARPS6KA3CHEK1 | |
| SCHEMBL19965866 | 0.69 | HRH3 (0.35) | ALDH1A1GAAPARP1RPS6KA2CYP2D6 | |
| SCHEMBL2898178 | 0.68 | HSD17B10 (0.49) | ALDH1A1GAARPS6KA3PARP1MAPKAPK2 | |
| SCHEMBL31607759 | 0.67 | NOTUM (0.34) | NOTUMALDH1A1CYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |