Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758090 | 0.91 | GPR119 (0.46) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL12136991 | 0.86 | NR1H2 (0.50) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL8426435 | 0.86 | NR1H2 (0.50) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL14514518 | 0.86 | NR1H2 (0.50) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL1318622 | 0.83 | GPR119 (0.46) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL31609153 | 0.83 | GPR119 (0.49) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL1318620 | 0.83 | GPR119 (0.46) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL20690682 | 0.83 | GPR119 (0.49) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL31609166 | 0.83 | GPR119 (0.49) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL20754454 | 0.82 | GPR119 (0.46) | GPR119NR1H2KDM4EPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4563579-A1 | MACROCYCLIC EGFR INHIBITOR, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2025-06-04 | — | — | EP | disclosed |