Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31609127 | 1.00 | GPR119 (0.45) | GPR119RECQLNR1H2KDM4EPKM | |
| SCHEMBL30758094 | 0.95 | HPGD (0.44) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL31609164 | 0.95 | EPHX1 (0.45) | GPR119NR1H2KDM4EPKMHPGD | |
| SCHEMBL31609166 | 0.86 | GPR119 (0.49) | GPR119RECQLNR1H2KDM4EPKM | |
| SCHEMBL20690682 | 0.86 | GPR119 (0.49) | GPR119RECQLNR1H2KDM4EPKM | |
| SCHEMBL31609153 | 0.86 | GPR119 (0.49) | GPR119RECQLNR1H2KDM4EPKM | |
| SCHEMBL1318622 | 0.86 | GPR119 (0.46) | GPR119RECQLNR1H2KDM4EPKM | |
| SCHEMBL1318620 | 0.86 | GPR119 (0.46) | GPR119RECQLNR1H2KDM4EPKM | |
| SCHEMBL16497005 | 0.86 | HPGD (0.48) | GPR119RECQLNR1H2KDM4EPKM | |
| SCHEMBL14514518 | 0.85 | NR1H2 (0.50) | GPR119RECQLNR1H2KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4563579-A1 | MACROCYCLIC EGFR INHIBITOR, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2025-06-04 | — | — | EP | disclosed |