⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809098 | 0.92 | — | — | |
| SCHEMBL2539591 | 0.89 | — | — | |
| SCHEMBL9020643 | 0.78 | — | — | |
| SCHEMBL795214 | 0.71 | — | — | |
| SCHEMBL600282 | 0.69 | BRD4 (0.52) | — | |
| SCHEMBL6043119 | 0.69 | — | — | |
| SCHEMBL9020634 | 0.69 | BRD4 (0.39) | — | |
| SCHEMBL2705725 | 0.69 | — | — | |
| SCHEMBL5839331 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL11513221 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133860-A1 | SYNTHESIS OF SMALL MOLECULE AGONISTS OF NEUROPTROPHIN | Oculis Operations Sàrl (CH) | 2024-06-27 | — | — | WO | claimed |
| WO-2023139084-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | claimed |
| US-20220387385-A1 | NEW TREATMENT REGIMENT FOR THE TREATMENT OF NEUROLOGICAL DISEASES OR CONDITIONS | ACCURE THERAPEUTICS, S.L. (ES) | 2022-12-08 | — | — | US | claimed |
| CN-115052595-A | Novel therapeutic methods for treating neurological diseases or disorders | 阿库尔疗法公司 | 2022-09-13 | — | — | CN | claimed |
| EP-3993784-A1 | COMBINATION THERAPY METHODS, COMPOSITIONS AND KITS | Accure Therapeutics, S.L. (ES) | 2022-05-11 | — | — | EP | claimed |
| EP-3458459-B1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AG (DE) | 2022-04-27 | — | — | EP | claimed |
| CN-114206329-A | Combination therapy methods, compositions and kits | 阿库尔疗法公司 | 2022-03-18 | — | — | CN | claimed |
| WO-2021084013-A1 | NEW TREATMENT REGIMEN FOR THE TREATMENT OF NEUROLOGICAL DISEASES OR CONDITIONS | BIONURE FARMA, S.L. (ES) | 2021-05-06 | — | — | WO | claimed |
| US-10981932-B2 | Macrocyclic indole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-20 | — | — | US | claimed |
| WO-2021001464-A1 | COMBINATION THERAPY METHODS, COMPOSITIONS AND KITS | BIONURE FARMA, S.L. (ES) | 2021-01-07 | — | — | WO | claimed |
| JP-H09503491-A | — | — | 1997-04-08 | — | — | JP | claimed |
| EP-0449191-B1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5438054-A | Antibacterial agent | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | claimed |
| WO-1995003303-A2 | AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY | STATE OF ISRAEL, REPRESENTED BY THE PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) | 1995-02-02 | — | — | WO | claimed |
| US-5358667-A | Comprising anionic cleanser, insoluble conditioner, polyhydric and quaternary ammonium compounds, suspension agent and carrier | HELENE CURTIS, INC. (US) | 1994-10-25 | — | — | US | claimed |
| EP-0452101-A2 | Spiro bridged and unbridged heterocyclic compounds | ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) | 1991-10-16 | — | — | EP | claimed |
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | claimed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | claimed |
| US-5053412-A | Central nervous system disorders | ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) | 1991-10-01 | — | — | US | claimed |
| EP-0097340-A2 | Piperazine derivatives, a process for preparing them and pharmaceutical compositions | FERRER INTERNACIONAL, S.A. (ES) | 1984-01-04 | — | — | EP | claimed |