Suramin

Suramin

SCHEMBL3161

Cc1ccc(C(=O)Nc2ccc(S(=O)(=O)O)c3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)cc1NC(=O)c1cccc(NC(=O)Nc2cccc(C(=O)Nc3cc(C(=O)Nc4ccc(S(=O)(=O)O)c5cc(S(=O)(=O)O)cc(S(=O)(=O)O)c45)ccc3C)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

FGF1

The experimentally established mechanism targets of Suramin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY11 Q96G91 9/20 1.00
RECQL P46063 5/20 1.00
KMT2A Q03164 5/20 1.00
HSD17B10 Q99714 5/20 1.00
TDP1 Q9NUW8 5/20 1.00
HPSE Q9Y251 5/20 1.00
TIMP3 P35625 4/20 1.00
MAPT P10636 4/20 1.00
PKM P14618 4/20 1.00
P2RX1 P51575 4/20 1.00
P2RX3 P56373 4/20 1.00
MEN1 O00255 3/20 1.00
USP2 O75604 2/20 1.00
BRCA1 P38398 2/20 1.00
SIRT2 Q8IXJ6 2/20 1.00
SIRT1 Q96EB6 2/20 1.00
ENPP3 O14638 1/20 1.00
ENTPD3 O75355 1/20 1.00
NR1I2 O75469 1/20 1.00
PRKD3 O94806 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Suramin SCHEMBL29357785 1.00 P2RY11 (1.00) P2RY11RECQLKMT2AHSD17B10TDP1
Suramin SCHEMBL30552218 1.00 P2RY11 (1.00) P2RY11RECQLKMT2AHSD17B10TDP1
Suramin SCHEMBL30312075 1.00 P2RY11 (1.00) P2RY11RECQLKMT2AHSD17B10TDP1
Suramin SCHEMBL29371906 1.00 P2RY11 (1.00) P2RY11RECQLKMT2AHSD17B10TDP1
SCHEMBL21686991 0.97 P2RY11 (0.95) P2RY11RECQLKMT2AHSD17B10TDP1
SCHEMBL20370854 0.95 P2RY11 (0.90) P2RY11RECQLKMT2AHSD17B10TDP1
SCHEMBL32686687 0.93 P2RY11 (0.87) P2RY11RECQLKMT2AHSD17B10TDP1
SCHEMBL16404704 0.93 P2RY11 (0.86) P2RY11RECQLKMT2AHSD17B10TDP1
SCHEMBL3358966 0.92 RECQL (1.00) P2RY11RECQLKMT2AHSD17B10TDP1
SCHEMBL30392305 0.92 RECQL (1.00) P2RY11RECQLKMT2AHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 38854 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106917-A1 EDIBLE TRANSMUCOSAL DRUG DELIVERY METHOD USING AN INTERMEDIATE CAPSULE AS A TEMPORARY VESSEL BioPhysics Pharma, Inc. (US) 2026-05-21 WO claimed
EP-4735045-A2 OXAZAPHOSPHORINE ANTIBODY DRUG CONJUGATES AND METHODS OF USE La Life Products, LLC (US) 2026-05-06 EP claimed
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
EP-4732908-A2 CANCER TREATMENT USING COMBINATIONS OF ERK AND RAF INHIBITORS Biomed Valley Discoveries, Inc. (US) 2026-04-29 EP claimed
EP-3209683-B1 FRAGMENTS OF SYNDECAN-2 HAVING ANTI-ANGIOGENIC ACTIVITY SYNDECPHARMA LTD (GB) 2026-04-29 EP claimed
US-20260109699-A1 AZOLE DERIVATIVES AS SHP2 INHIBITORS IRBM S.P.A. (IT) 2026-04-23 US claimed
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 US claimed
EP-4714452-A1 METHODS FOR TREATING SARS COV-2 INFECTIONS Gilead Sciences, Inc. (US) 2026-03-25 EP claimed
US-12582621-B2 Compositions and methods for delivering pharmaceutical agents Arizona Board of Regents on Behalf of the Universityof Arizona (US) 2026-03-24 US claimed
EP-4426280-B1 PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS GURBA ALEXANDRE (CH) 2026-03-18 EP claimed
WO-1989011277-A2 PORPHYRIN AND PHTHALOCYANINE ANTIVIRAL COMPOSITIONS GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) 1989-11-30 WO claimed
EP-0342203-A1 2',3' DIDEOXYRIBOFURANOXIDE DERIVATIVES. NYCOMED AS (NO) 1989-11-23 EP claimed
EP-0263873-A4 ANTI-PATHOGENIC BLOOD COLLECTION SYSTEM AND METHOD. AL-SIOUFI HABIB 1989-07-11 EP claimed
WO-1988007532-A1 2',3' DIDEOXYRIBOFURANOXIDE DERIVATIVES NYCOMED A.S. (NO) 1988-10-06 WO claimed
EP-0263873-A1 ANTI-PATHOGENIC BLOOD COLLECTION SYSTEM AND METHOD AL-SIOUFI, Habib (US) 1988-04-20 EP claimed
US-4737521-A Suramin sodium for use as an immunostimulant BAYER AKTIENGESELLSCHAFT (DE) 1988-04-12 US claimed
WO-1987006119-A1 ANTI-PATHOGENIC BLOOD COLLECTION SYSTEM AND METHOD AL SIOUFI HABIB 1987-10-22 WO claimed
EP-0183352-A2 Use of suramin for clinical treatment of infection with any of the members of the family of human-t-cell leukemia (htvl) viruses including lymphadenopathy virus (lav) THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1986-06-04 EP claimed
WO-1986002266-A1 USE OF SURAMIN FOR CLINICAL TREATMENT OF INFECTION WITH ANY OF THE MEMBERS OF THE FAMILY OF HUMAN T-CELL LEUKEMIA (HTLV) VIRUSES INCLUDING LYMPHADENOPATHY VIRUS (LAV) UNITED STATES OF AMERICA, REPRESENTED BY THE UNITE (US) 1986-04-24 WO claimed
US-4218535-A Determination of enzyme substrate concentration BECKMAN INSTRUMENTS, INC. (US) 1980-08-19 US claimed