Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | HCK | P08631 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24008132 | 0.85 | RET (0.34) | MAP3K12ALDH1A1KDM4ELMNAKCNH2 | |
| SCHEMBL27193361 | 0.80 | MAP3K12 (0.42) | MAP3K12PIK3CDABL1EGFRHCK | |
| SCHEMBL27193654 | 0.80 | MAP3K12 (0.42) | MAP3K12PIK3CDABL1EGFRHCK | |
| SCHEMBL24567236 | 0.80 | MAP3K12 (0.42) | MAP3K12PIK3CDABL1EGFRHCK | |
| SCHEMBL25647108 | 0.76 | GABRA2 (0.38) | NR3C2MAP3K12HPGDALDH1A1KDM4E | |
| SCHEMBL24566083 | 0.75 | MGAT2 (0.31) | — | |
| SCHEMBL24007613 | 0.74 | STS (0.44) | KDM4EPIK3CAMTORPIK3CGTHRB | |
| SCHEMBL25599957 | 0.73 | MAP3K12 (0.30) | MAP3K12 | |
| SCHEMBL31052495 | 0.73 | HPGD (0.43) | HPGDMPOALDH1A1KDM4EGAA | |
| SCHEMBL16794528 | 0.72 | NR3C2 (0.45) | NR3C2MAP3K12HPGDMPOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025119300-A1 | MYT1 KINASE INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 广东东阳光药业股份有限公司 | 2025-06-12 | — | — | WO | disclosed |
| CN-120118088-A | Myt1 kinase inhibitor compounds, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业股份有限公司 | 2025-06-10 | — | — | CN | disclosed |