SCHEMBL31613829

SCHEMBL31613829

Cc1ccc2c(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)cccc2c1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31613839 0.91 KIF18A (0.68) KIF18A
SCHEMBL31613832 0.91 KIF18A (0.72) KIF18A
SCHEMBL30842155 0.90 KIF18A (0.65) KIF18A
SCHEMBL31613831 0.88 KIF18A (0.67) KIF18A
SCHEMBL31613830 0.85 KIF18A (0.72) KIF18A
SCHEMBL31613836 0.84 KIF18A (0.70) KIF18A
SCHEMBL31613825 0.84 KIF18A (0.68) KIF18A
SCHEMBL31167205 0.84 KIF18A (0.64) KIF18A
SCHEMBL31694775 0.81 KIF18A (0.61) KIF18A
SCHEMBL31694760 0.81 KIF18A (0.63) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4567032-A1 KIF18A INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2025-06-11 — — EP disclosed
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