SCHEMBL31613835

SCHEMBL31613835

O=C(Nc1ccnc2c1nc1n2CCC1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30842163 0.89 KIF18A (0.63) KIF18A
SCHEMBL30842125 0.87 KIF18A (0.62) KIF18A
SCHEMBL30842182 0.86 KIF18A (0.63) KIF18A
SCHEMBL31613817 0.85 KIF18A (0.60) KIF18A
SCHEMBL30842148 0.82 KIF18A (0.62) KIF18A
SCHEMBL31613822 0.81 KIF18A (0.59) KIF18A
SCHEMBL31613813 0.81 KIF18A (0.67) KIF18A
SCHEMBL31613838 0.81 KIF18A (0.59) KIF18A
SCHEMBL31694776 0.79 KIF18A (0.62) KIF18A
SCHEMBL31613820 0.79 KIF18A (0.60) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4567032-A1 KIF18A INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2025-06-11 — — EP disclosed
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