Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | LIG1 | P18858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722067 | 0.82 | TTR (0.68) | TTRGLAAPEX1NPC1RAB9A | |
| SCHEMBL19834868 | 0.82 | TTR (0.68) | TTRGLAAPEX1NPC1RAB9A | |
| SCHEMBL2162290 | 0.81 | TTR (0.66) | TTRGLAAPEX1NPC1RAB9A | |
| SCHEMBL13402297 | 0.79 | TTR (1.00) | TTRGLAAPEX1NPC1RAB9A | |
| SCHEMBL13365129 | 0.79 | CYP4F2 (0.48) | TTRGLAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL25275728 | 0.78 | L3MBTL1 (0.73) | TTRGLAAPEX1NPC1RAB9A | |
| SCHEMBL19321049 | 0.78 | TTR (0.62) | TTRGLAAPEX1NPC1RAB9A | |
| SCHEMBL19326048 | 0.77 | TTR (0.60) | TTRGLAAPEX1NPC1RAB9A | |
| SCHEMBL13402279 | 0.77 | APEX1 (1.00) | TTRGLAAPEX1NPC1RAB9A | |
| SCHEMBL15878084 | 0.75 | APEX1 (0.58) | TTRGLAAPEX1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136764-A | Pleuromutilin derivative capable of inhibiting bacterial hydrogen sulfide biosynthesis and preparation method and application thereof | 陕西科技大学 | 2025-06-13 | — | — | CN | disclosed |