SCHEMBL31619863

SCHEMBL31619863

O=C1CCC(Nc2cccc(NC(=O)C3CC3)c2)C(=O)N1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 16/20 0.64
▸ CRBN Q96SW2 16/20 0.64
▸ GAA P10253 2/20 0.48
▸ USP2 O75604 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ MAPK14 Q16539 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31174861 0.99 DDB1 (0.63) DDB1CRBNGAAUSP2LMNA
SCHEMBL22117962 0.87 DDB1 (0.68) DDB1CRBN
SCHEMBL22118082 0.86 CRBN (0.66) DDB1CRBN
SCHEMBL31071533 0.85 CRBN (0.62) DDB1CRBN
SCHEMBL31071522 0.85 CRBN (0.62) DDB1CRBN
SCHEMBL31071520 0.85 CRBN (0.62) DDB1CRBN
Hydrochloric Acid SCHEMBL30338604 0.85 CRBN (0.64) DDB1CRBN
Hydrochloric Acid SCHEMBL30338009 0.85 CRBN (0.64) DDB1CRBN
Bromide SCHEMBL30338367 0.85 CRBN (0.64) DDB1CRBN
Hydrochloric Acid SCHEMBL30338379 0.85 CRBN (0.64) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120152718-A Combination therapy with substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds 百时美施贵宝公司 2025-06-13 — — CN claimed
CN-120152718-A Combination therapy with substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds 百时美施贵宝公司 2025-06-13 — — CN disclosed
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