Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27253669 | 1.00 | PGK1 (0.64) | PGK1MEN1KMT2AHTTJAK2 | |
| SCHEMBL20266994 | 0.89 | PGK1 (0.65) | PGK1MEN1KMT2AHTTIRAK4 | |
| SCHEMBL3643238 | 0.83 | EGFR (0.65) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL7262064 | 0.81 | PDE5A (0.58) | PGK1MEN1KMT2AHTTKCNA5 | |
| SCHEMBL4089465 | 0.80 | PDE5A (0.69) | MEN1KMT2AHTTJAK2IGF1R | |
| SCHEMBL31620265 | 0.80 | HTT (0.62) | PGK1MEN1KMT2AHTTKDM4E | |
| SCHEMBL27253658 | 0.80 | HTT (0.62) | PGK1MEN1KMT2AHTTKDM4E | |
| SCHEMBL25354458 | 0.80 | MAPK1 (0.60) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL1291750 | 0.78 | PGK1 (1.00) | PGK1MEN1KMT2AHTTGSK3B | |
| SCHEMBL3112150 | 0.77 | MEN1 (0.66) | MEN1KMT2AHTTCCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152965-A | Quinazoline derivatives | 国立大学法人京都大学 | 2025-06-13 | — | — | CN | claimed |
| EP-4617268-A1 | QUINAZOLINE DERIVATIVES | Kyoto University (JP) | 2025-09-17 | — | — | EP | disclosed |
| CN-120152965-A | Quinazoline derivatives | 国立大学法人京都大学 | 2025-06-13 | — | — | CN | disclosed |